The effect of Shikonin on the expression of apoptosis-related miRNAs and their putative targets in human kidney cancer cells

A tétel rövid nézete
dc.contributor.advisorSzabó, Zsuzsanna
dc.contributor.advisordeptDebreceni Egyetem::Gyógyszerésztudományi Kar
dc.contributor.authorRahimian, Mana
dc.contributor.departmentDE--Gyógyszerésztudományi Kar
dc.contributor.opponentHalmos, Gábor
dc.contributor.opponentdeptDebreceni Egyetem::Gyógyszerésztudományi Kar
dc.date.accessioned2023-05-03T08:09:50Z
dc.date.available2023-05-03T08:09:50Z
dc.date.created2023-03-01
dc.description.abstractMicroRNAs are a newly explored field in the treatment of kidney cancer. Renal cell carcinoma is a global, stealthy illness with over 400,000 new cases and over 170,000 deaths annually, placing it among the top 10 most prevalent cancers. MicroRNAs are a newly explored field in the treatment of kidney cancer. In this thesis, we are investigating the potential role of microRNAs (specifically hsa-miR-15a, and hsa-miR-99a-5p) in the development or suppression of cancer in renal cell lines, describing their apoptotic pathways and their potential use as biomarkers for diagnosis of RCC or therapeutic and preventive use in targeted therapy of malignant RCC. Our main goal is to improve familiarity with microRNAs as much as possible to increase the rate of renal cell cancer recovery.
dc.description.correctorLB
dc.description.coursegyógyszerész
dc.description.courselangangol
dc.description.coursespecOrvosbiológia-farmakológia
dc.description.degreeegységes, osztatlan
dc.format.extent52
dc.identifier.urihttps://hdl.handle.net/2437/351539
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectoncology
dc.subjecttarget therapy
dc.subjectbiopharmacy
dc.subjectrenal cell cancer
dc.subjectshikonin
dc.subject.dspaceDEENK Témalista::Biológiai tudományok
dc.titleThe effect of Shikonin on the expression of apoptosis-related miRNAs and their putative targets in human kidney cancer cells
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Gyűjtemények
Theses (Faculty of Pharmacy)