Pharmacological management of preterm delivery.

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dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorNguyen, Duy Hong Khanh
dc.contributor.departmentDE--Gyógyszerésztudományi Karhu_HU
dc.contributor.opponentDrimba, László
dc.contributor.opponentSzentmiklósi, József András
dc.contributor.opponentdeptKenézy Kórház Központi Aneszteziológiai és Intenzív Terápiás Osztályhu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.date.accessioned2019-01-31T12:06:58Z
dc.date.available2019-01-31T12:06:58Z
dc.date.created2018-06-15
dc.description.abstractPrematurity occurs when regular contractions begin to open your cervix before 37 weeks of pregnancy while a full-term pregnancy should last about 40 weeks. Both morbidity and mortality rates are inversely related to gestational age at delivery and each day of delay, particularly before 28 weeks of gestation, increases the survival.The available treatment options are symptomatic, rather than causally directed. Initially, preventive treatment with progesterone can lower the rate of PTL in high-risk groups significantly. Furthermore, between 24 and 33 weeks of gestation, the benefits of tocolytic therapy generally outweigh the risk of maternal, fetal, or both complications and these agents should be initiated provided no contraindications exist. A variety of tocolytic drugs with different mechanisms of action (betamimetics, oxytocin antagonists, calcium-channel blockers, nitric oxide donors, magnesium sulfate, and prostaglandin synthesis inhibitors) can be used for individualized tocolytic treatment. Furthermore, progesterones have proved the role in prolongation of gestation in PTL. Nevertheless, premature rupture of the membranes is an indication for antibiotics. Additionally, antenatal steroid administration could prevent respiratory distress syndrome in newborn effectively.hu_HU
dc.description.correctorLB
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.coursespecOrvosbiológia-farmakológiahu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent46hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/263471
dc.language.isoenhu_HU
dc.subjectMDhu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titlePharmacological management of preterm delivery.hu_HU
dc.title.translatedKoraszülött gyógyszeres kezelés.hu_HU
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