Cellular Interaction Partners of HIV-2's Viral Protein X

dc.contributor.advisorMahdi, Mohamed
dc.contributor.advisordeptDepartment of Biochemistry and Molecular Biologyhu_HU
dc.contributor.authorAllawi, Jane
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentDemény, Máté
dc.contributor.opponentdeptDepartment of Medical Chemistryhu_HU
dc.date.accessioned2020-07-28T12:52:08Z
dc.date.available2020-07-28T12:52:08Z
dc.date.created2020-07-21
dc.description.abstractHIV-2's viral protein X was discovered to inhibit the viral replication of HIV-1. The thesis discusses and proposes some of the proteins that interact with vpX to further understand the its role in the prolonged latency period of HIV-2. The methods used to examine this were Proximity Ligation Assay, co-Immunoprecipitation, and Western Blot. Through the PLA, it was seen than CTBP-2, a known co-repressor, interacts with the vpX. The role of vpX is under further examination to understand its mechanism in the viral life cycle of HIV-2.hu_HU
dc.description.coursemolekuláris biológiahu_HU
dc.description.courselangangolhu_HU
dc.description.coursespecBiokémia-genomikahu_HU
dc.description.degreeMSc/MAhu_HU
dc.format.extent25hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/291475
dc.language.isoenhu_HU
dc.subjectHIV-2hu_HU
dc.subject.dspaceDEENK Témalista::Biológiai tudományokhu_HU
dc.titleCellular Interaction Partners of HIV-2's Viral Protein Xhu_HU
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