Pharmacological basis of growth hormone therapy

A tétel rövid nézete
dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézet
dc.contributor.authorMagal, Natali
dc.contributor.departmentDE--Általános Orvostudományi Kar
dc.contributor.opponentMegyeri, Attila
dc.contributor.opponentDrimba, László
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézet
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Aneszteziológiai és Intenzív Terápiás Tanszék
dc.date.accessioned2023-07-25T10:40:08Z
dc.date.available2023-07-25T10:40:08Z
dc.date.created2023-06-02
dc.description.abstractOn this dissertation, the efficacy, safety, and clinical applications of rhGH therapy were investigated as a treatment of many diseases and conditions. GH plays a crucial part in normal growth, metabolism, and general development. Any abnormality in its function or secretion can lead to many systemic manifestations. This thesis provides a comprehensive overview GH therapy: starting with historical background, explaining the mechanism of action and its various clinical indications for the treatment. In addition, it demonstrates the potential adverse and the possible outcomes of the therapy. The thesis also discusses the specific medical conditions that may require GH therapy, such as GHD in pediatric and adult patients, Prader Willi syndrome, Turner syndrome, chronic kidney disease, and more. It focuses the significance of these conditions, emphasizing the importance of the timely and appropriate intervention of the therapy. Furthermore, this thesis demonstrates the possible adverse effects and risk factors that is associated with GH therapy together with its misuse as enhancing physical performance drug by many athletes up to this day. In addition, it explains briefly about the administration method of the treatment. It might be concluded, that since rhGH introduction in 1985 it’s use have grown significantly, spanning through a whole repertoire of diseases, showing great results with significant improvement in both pediatric and adult patients.
dc.description.correctorLB
dc.description.courseáltalános orvos
dc.description.courselangangol
dc.description.degreeegységes, osztatlan
dc.format.extent57
dc.identifier.urihttps://hdl.handle.net/2437/357854
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectgrowth hormone
dc.subjectIGF-1
dc.subjectshort stature
dc.subjectpediatrics
dc.subjectTurner
dc.subjectdopping agents
dc.subject.dspaceDEENK Témalista::Orvostudomány::Farmakológia
dc.titlePharmacological basis of growth hormone therapy
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Gyűjtemények
Theses (Faculty of Medicine)