Effects of Acute Heat Stress on a Newly Established Chicken Hepatocyte—Nonparenchymal Cell Co-Culture Model

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dc.contributor.authorMackei, Máté
dc.contributor.authorMolnár, Andor
dc.contributor.authorNagy, Szabolcs
dc.contributor.authorPál, László
dc.contributor.authorKővágó, Csaba
dc.contributor.authorGálfi, Péter
dc.contributor.authorDublecz, Károly
dc.contributor.authorHusvéth, Ferenc
dc.contributor.authorNeogrády, Zsuzsanna
dc.contributor.authorMátis, Gábor
dc.contributor.statusegyetemi oktató, kutatóhu_HU
dc.coverage.temporal2020.04.30.hu_HU
dc.date.accessioned2021-06-17T10:07:19Z
dc.date.available2021-06-17T10:07:19Z
dc.description.abstractAmong many environmental stress factors, heat stress can intensely deteriorate animal health, welfare, and productivity in poultry farming. In the present study, a novel cell culture comprised of different liver cell types from chickens was established to serve as a model for studying the effects of acute heat stress. Short, 1 h heat exposure strongly affected liver cells by increasing metabolism, triggering oxidative stress, and decreasing the generation of certain mediatory molecules of the cellular stress response. However, these alterations were normalized after 2 h of heat stress, suggesting a fast adaptation of liver cells. The results of this study underline the impact of short-term heat stress as a potential harmful factor affecting liver function in chickens.hu_HU
dc.format.extent15hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/311240
dc.language.isoenhu_HU
dc.subjectheat stresshu_HU
dc.subjectliverhu_HU
dc.subjectcell culturehu_HU
dc.subjectheat shock proteinshu_HU
dc.subjectpro-inflammatory cytokineshu_HU
dc.subjectoxidative stresshu_HU
dc.subjectbroiler chickenhu_HU
dc.subject.disciplinetudományterületek::állattenyésztési tudományokhu_HU
dc.titleEffects of Acute Heat Stress on a Newly Established Chicken Hepatocyte—Nonparenchymal Cell Co-Culture Modelhu_HU
dc.typeidegen nyelvű peer review publikációhu_HU
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