The effects of SGLT2 inhibitor side chain structure on its function and side effects

A tétel rövid nézete
dc.contributor.advisorUray, Karen
dc.contributor.advisorDocsa, Tibor
dc.contributor.authorNuñez de la Rosa, Ana Karen
dc.contributor.departmentDE--Természettudományi és Technológiai Kar--Biotechnológiai Intézet
dc.date.accessioned2022-11-15T13:50:23Z
dc.date.available2022-11-15T13:50:23Z
dc.date.created2022-11-15
dc.description.abstractType 2 diabetes mellitus (T2DM) is a chronic disease characterized by hyperglycemia. The pathophysiology of T2DM is complex but it is known that cells cannot use insulin effectively. The initial treatment for T2DM focuses on a healthy lifestyle, however, if this does not reduce glucose blood levels, oral medication is needed, such as SGLT2 inhibitors. The lack of adherence to the antidiabetic treatment is generally due to the medication's side effects. This increases the rates of complications in diabetic patients. Thus, the main objective of this diploma work is to study how SGLT2 inhibitors' structure may or may not affect smooth muscle intestinal activity and apply this knowledge to avoid its side effects.
dc.description.courseBiochemical Engineering
dc.description.degreeBSc/BA
dc.format.extent35
dc.identifier.urihttps://hdl.handle.net/2437/340091
dc.language.isoen
dc.subjectSGLT2 inhibitor
dc.subjectSGLT
dc.subjectType 2 diabetes mellitus
dc.subject.dspaceDEENK Témalista::Orvostudomány::Orvosi vegytan
dc.titleThe effects of SGLT2 inhibitor side chain structure on its function and side effects
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Gyűjtemények
Theses (Faculty of Science and Technology)