Long COVID Syndrome and Cardiovascular Manifestations: A Systematic Review and Meta-Analysis

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dc.contributor.authorShrestha, Abhigan Babu
dc.contributor.authorMehta, Aashna
dc.contributor.authorPokharel, Pashupati
dc.contributor.authorMishra, Aakash
dc.contributor.authorAdhikari, Lukash
dc.contributor.authorShrestha, Sajina
dc.contributor.authorYadav, Randhir Sagar
dc.contributor.authorKhanal, Surakshya
dc.contributor.authorSah, Ranjit
dc.contributor.authorNowrouzi-Kia, Behdin
dc.contributor.authorPadhi, Bijaya Kumar
dc.contributor.authorChattu, Vijay Kumar
dc.contributor.authorMehta, Aashna (2023-) (xxx)
dc.contributor.submitterdepSebészeti Műtéttani Tanszék -- 36
dc.contributor.submitterdepÁOK
dc.contributor.submitterdepDebreceni Egyetem
dc.date.accessioned2023-07-13T13:22:36Z
dc.date.available2023-07-13T13:22:36Z
dc.date.oa2023-08-04
dc.date.updated2023-07-13T13:22:35Z
dc.description.abstract(1) Background: Long COVID syndrome is a significant cause of morbidity in COVID-19 patients who remain symptomatic with varied clinical presentations beyond three weeks. Furthermore, the relevance of considering cardiovascular outcomes in post-COVID-19 syndrome is important in the current COVID-19 pandemic; (2) Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed for this systematic review and meta-analysis. Systematic searches were conducted from multiple databases without language restrictions until October 8, 2022, to find studies evaluating cardiovascular outcomes such as arrhythmias, myocardium and pericardium diseases, coronary vessel disease, and thromboembolic disorders in post-COVID cases. The pooled odds ratio (OR), and standard mean difference (SMD) with their corresponding 95% confidence intervals (CI) were computed to find the association; (3) Results: Altogether, seven studies with a total of 8,126,462 (cases: 1,321,305; controls: 6,805,157) participants were included in the meta-analysis. Pooled odds ratios of cardiovascular outcomes were significantly higher in post-COVID cases (OR > 1, p < 0.05) than in controls. However, the mortality (OR: 4.76, p = 0.13), and heart rate variability (SMD: -0.06, p = 0.91) between cases and controls were not statistically significant; (4) Conclusions: Significant cardiovascular sequelae in long COVID syndrome highlight the importance of careful cardiac monitoring of COVID-19 patients in the post-COVID phase to address cardiovascular complications as soon as possible; larger-scale prospective studies are required for accurate estimation.
dc.description.correctorkzs
dc.identifier.citationDiagnostics. -13 : 3 (2023), p. 1-8 (cikkazonosító)491. -Diagnostics. -2075-4418. -2075-4418
dc.identifier.doi10.3390/diagnostics13030491
dc.identifier.issn2075-4418. -
dc.identifier.issn2075-4418
dc.identifier.opachttps://ebib.lib.unideb.hu/ebib/CorvinaWeb?action=cclfind&resultview=long&ccltext=idno+BIBFORM113380
dc.identifier.urihttps://hdl.handle.net/2437/357519
dc.identifier.urlhttps://www.mdpi.com/2075-4418/13/3/491
dc.languageeng
dc.rights.accessopen access journal
dc.rights.ownerszerző
dc.subject.otheridegen nyelvű folyóiratközlemény külföldi lapban
dc.subject.othercardiovascular outcome; COVID-19; long COVID; post-COVID syndrome; dysrhythmias; systematic review and meta-analysis; SARS-CoV-2; tachycardia
dc.titleLong COVID Syndrome and Cardiovascular Manifestations: A Systematic Review and Meta-Analysis
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