Reperfusion Therapies in Acute Ischemic Stroke Beyond the Conventional Time Window

A tétel rövid nézete
dc.contributor.advisorOláh, László
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Neurológiai Klinikahu_HU
dc.contributor.authorMansour, Mohammad Naser Mohammad
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentFekete, Klára
dc.contributor.opponentTóth, Judit
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Neurológiai Klinikahu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Radiológiai Klinikahu_HU
dc.date.accessioned2022-08-18T08:22:32Z
dc.date.available2022-08-18T08:22:32Z
dc.date.created2022-06-14
dc.description.abstractThe aim of this thesis is to review the scientific literature on possibilities of reperfusion therapies for patients who present with unknown time of stroke onset, and those with stroke onset beyond the conventional 4.5-6 hour time window. Beyond the conventional time window, the eligibility of patients for intravenous thrombolysis or mechanical endovascular thrombectomy, the two main therapeutic procedures, is decided based on the concept of penumbral imaging. Penumbral imaging identifies patients with hypoperfused but viable brain tissue, who could possibly benefit from reperfusion. On the other hand, clock-based DWI-FLAIR magnetic resonance imaging can detect stroke that has occurred within 4.5 hours in patients with unknown time of onset, including patients who awaken with stroke. The introduction of penumbral imaging and MRI-based tissue clocking as imaging biomarkers for stroke has revolutionized stroke therapy, potentially allowing for personalized treatment of eligible stroke patients.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent38hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/336564
dc.language.isoenhu_HU
dc.subjectAcute Ischemic Strokehu_HU
dc.subjectReperfusion Therapyhu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titleReperfusion Therapies in Acute Ischemic Stroke Beyond the Conventional Time Windowhu_HU
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Gyűjtemények
Theses (Faculty of Medicine)