This thesis offers a detailed analysis of the hemorheological effects of various anticoagulants, elucidating the complex interactions between these agents and blood rheology. It explains blood coagulation processes and categorizes anticoagulants into four main types: Vitamin K Antagonists, heparins (UFH, LMWH, ultra-low-molecular-weight heparin), direct inhibitors, and miscellaneous agents. The study explores how different anticoagulants, such as UFH and LMWH, interact with antithrombin to inactivate clotting factors, while direct inhibitors work independently. Key hemorheological parameters such as blood viscosity, erythrocyte aggregation, and red blood cell deformability are examined, highlighting their importance in tissue perfusion and microvascular function. The research also emphasizes the role of micro-rheology in assessing blood coagulation and the impact of anticoagulants on red blood cell elasticity and clot dynamics. Findings from studies on heparin and argatroban's effects on blood viscosity and red blood cell behavior support the thesis, enhancing therapeutic strategies and advancing anticoagulant therapy in clinical practice.