Synthesis of mannobioside containing 1,4 thio linkage for lectin binding studies

dc.contributor.advisor	Hevesi-Mezo , Erika
dc.contributor.advisordept	Gyógyszerésztudományi Kar
dc.contributor.author	Miriam Suder, Agara
dc.contributor.department	DE--Gyógyszerésztudományi Kar
dc.date.accessioned	2026-05-04T13:03:13Z
dc.date.available	2026-05-04T13:03:13Z
dc.date.created	2026-02-16
dc.description.abstract	Mannobiosides are dimers of mannose that bind more strongly to lectins than single mannose units. They are useful for studying immune recognition, bacterial adhesion, and lectin–carbohydrate interactions. To improve stability, the glycosidic oxygen can be replaced with sulfur to form thiomannobiosides. These modified molecules remain biologically active while being more resistant to enzymatic breakdown. The thesis focuses on synthesizing a 1,4-thio-linked mannobioside using controlled chemical methods. However, the synthesis is difficult, and the final target compound was not successfully obtained.
dc.description.course	gyógyszerész
dc.description.courselang	angol
dc.description.degree	egységes, osztatlan
dc.format.extent	33
dc.identifier.uri	https://hdl.handle.net/2437/406774
dc.language.iso	en
dc.rights.info	Hozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subject	Lectin , carbohydrate, synthesis
dc.subject.dspace	Chemistry
dc.title	Synthesis of mannobioside containing 1,4 thio linkage for lectin binding studies

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