Synthetic Derivatives of C. sativa as Potential Drug Candidates Against Cutaneous Melanoma Cells

dc.contributor.advisorSzabó , Erzsébet
dc.contributor.advisordeptGyógyszerésztudományi Kar
dc.contributor.authorGholami, Soheyla
dc.contributor.departmentDE--Gyógyszerésztudományi Kar
dc.contributor.opponentTosaki, Agnes
dc.contributor.opponentSzabó, Zsuzsanna
dc.contributor.opponentdeptGyógyszerésztudományi Kar
dc.date.accessioned2025-04-24T07:05:52Z
dc.date.available2025-04-24T07:05:52Z
dc.date.created2025-04-23
dc.description.abstractThis study looks at two synthetic compounds made from Cannabis sativa, named PFD-11A and PFD-35/II, and how they affect skin cancer cells called melanoma. These cancer cells are usually hard to treat, so new drug options are needed. The researchers tested the compounds on two different melanoma cell lines and found that PFD-35/II was more effective at killing the cells. The drugs reduced the cancer cells’ ability to grow and survive over time. They also seemed to work by triggering processes like autophagy and cell death. The findings suggest these compounds could be useful for treating melanoma, but more research, especially in animals, is needed to confirm this.
dc.description.coursegyógyszerész
dc.description.courselangangol
dc.description.degreeMSc/MA
dc.format.extent41
dc.identifier.urihttps://hdl.handle.net/2437/389341
dc.language.isoen
dc.rights.infoHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectMelanoma, C. sativa, synthetic
dc.subject.dspaceBiology
dc.titleSynthetic Derivatives of C. sativa as Potential Drug Candidates Against Cutaneous Melanoma Cells
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