Pharmacological Interventions for Enhancing Mitochondrial Function and Energy Production in Athletes
| dc.contributor.advisor | Priksz, Dániel | |
| dc.contributor.advisordept | Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézet | |
| dc.contributor.author | Al Aqrabawi, Laith | |
| dc.contributor.department | DE--Általános Orvostudományi Kar | |
| dc.contributor.opponent | Varga, Balázs | |
| dc.contributor.opponent | Pető, Ágota | |
| dc.contributor.opponentdept | Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézet | |
| dc.contributor.opponentdept | Gyógyszerésztudományi Kar::Gyógyszertechnológiai Tanszék | |
| dc.date.accessioned | 2026-05-20T08:03:52Z | |
| dc.date.available | 2026-05-20T08:03:52Z | |
| dc.date.created | 2026-05-15 | |
| dc.description.abstract | Investigation of pharmacotherapeutic agents with the goal of enhancing mitochondrial function, ATP production, and exercise performance in athletes. The agents reviewed include Urolithin A, CoQ10, MitoQ, NMN, Creatine, NR, Elamipretide, Mitochondrial-derived peptides, exercise mimetics, and classical doping agents. The agents Urolithin A, MitoQ, NMN, and Creatine had the clearest human and/or athlete related evidence, although most studies are small and short term. CoQ10 and MitoQ may support oxidative stress reduction and recovery biomarkers, but evidence for direct performance enhancement remains limited. Elamipretide and mitochondrial-derived peptides are not yet practical athlete therapies, although they are promising mechanistic and disease based concept. Overall, mitochondrial-targeted therapy is promising for athletic use, but larger and longer term studies are required, especially with long term safety data and responder analysis. | |
| dc.description.course | általános orvos | |
| dc.description.courselang | angol | |
| dc.description.degree | egységes, osztatlan | |
| dc.format.extent | 27 | |
| dc.identifier.uri | https://hdl.handle.net/2437/407193 | |
| dc.language.iso | en | |
| dc.rights.info | Hozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében. | |
| dc.subject | Pharmacology | |
| dc.subject | Pharmacotherapy | |
| dc.subject | Mitochondria | |
| dc.subject.dspace | Medicine::Pharmacology | |
| dc.title | Pharmacological Interventions for Enhancing Mitochondrial Function and Energy Production in Athletes |
Fájlok
Eredeti köteg (ORIGINAL bundle)
1 - 1 (Összesen 1)
Nincs kép
- Név:
- Thesis_Al Aqrabawi Laith Mohammad Ali 2026 - Finalized.pdf
- Méret:
- 1.04 MB
- Formátum:
- Adobe Portable Document Format
- Leírás:
Engedélyek köteg
1 - 1 (Összesen 1)
Nincs kép
- Név:
- license.txt
- Méret:
- 1.94 KB
- Formátum:
- Item-specific license agreed upon to submission
- Leírás: