Airway Microbiome; Allergy, Asthma

dc.contributor.advisorBácsi, Attila
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Immunológiai Intézethu_HU
dc.contributor.authorBashir, Maryam
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentSzabó, Judit
dc.contributor.opponentMajoros, László
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Orvosi Mikrobiológiai Intézethu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Orvosi Mikrobiológiai Intézethu_HU
dc.date.accessioned2016-09-16T08:01:08Z
dc.date.available2016-09-16T08:01:08Z
dc.date.created2016-07-14
dc.description.abstractThe rate at which the prevalence of allergy keeps rising globally poses a threat to health and economic development.Various parts of the immune system are involved in this process and some delineated genetic and environmental factors seem to contribute to the development of allergy. The gut microbiome contains the largest collection of bacteria in the human body that interacts with the immune system, subsequently playing a role in contribution to immunogenic tolerance.Altered diversity of the gut microbiome during infancy as well as colonization with specific pathogenic and non-pathogenic bacteria has been linked with an elevated risk for allergy and asthma.Diversity within the airway microbiome reflects either a diseased or healthy state. Interesting differences have been found between microbial compositions in the airways of healthy and diseased people, such as patients with allergic asthma.Relationships between the disease severity, co-morbidities, control status and use of medication suggest that a number of interactions between the airway microbiome, host immunity and potential exposures likely have roles in the type and degree of airway inflammation and could possibly clarify some of the heterogeneity expressed in some allergic diseases like asthma.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent30hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/230489
dc.language.isoenhu_HU
dc.subjectMicrobiomehu_HU
dc.subjectAsthmahu_HU
dc.subjectAllergyhu_HU
dc.subjectAirwayshu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titleAirway Microbiome; Allergy, Asthmahu_HU
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