There are significant processes in Africa quest for regional integration although it is proceeding very slowly. On the whole it is imperative for Africans to be clear and have consensus on what they understand by regional integration and also to define or redefine it in a way that best serve them. Regional integration anywhere in the world cannot be achieved by mere setting up frame works and signing protocols and treaties as the process of integration can never be without challenges but the benefit of it is fundamental to Africa growth and development as it is accruable to long term while its cost will be met short by member countries. These challenges of consolidating regional integration have shaped the responses and commitments of Africa leaders having recognized the changing world requires greater collective actions and have therefore embraced deeper regional integration. There were 70 respondents who were consulted for the research using the questionnaire method through the internet. The questions raised were structured and closed questions which allowed for choosing any of the options provided as responses. The research was carried out to examine the impact of regional economic integration in Africa using the NEPAD initiative.