Management of Bleeding Disorders and Coagulopathies in the Surgical Practice
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The management of bleeding disorders and coagulopathies in the perioperative setting is a vital part of surgical care as it significantly impacts patient safety and outcome. Successful management necessitates an extensive comprehension of the bleeding mechanisms and the modes of action of the available interventions. Coagulation conditions can be broadly classified into primary coagulopathies and secondary coagulopathies. The former occurs due to a deficiency or dysfunction of clotting factors, while the latter results from an imbalance of procoagulant and anticoagulant pathways. The main objectives of perioperative management are to correct underlying coagulopathies, minimize surgical blood loss, and promote optimal hemostasis during and after the procedure. The diagnosis of a bleeding disorder is crucial for appropriate management. A comprehensive preoperative evaluation, including CBC, coagulation panel, and other necessary tests, is imperative to achieve these goals. Although there are no standardized guidelines, local recommendations for strategies may be available. Surgery can affect hemostasis by initiating coagulation and impairing fibrinolysis, therefore the timing, type of procedure, and underlying bleeding disorder must be considered when planning surgery.