Antibody Mediated Rejection (ABMR) after Kidney Transplantation: Diagnostic and Prognostic Markers of Hemostasis and Endothelial Cell Damage

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dc.contributor.advisorBagoly, Zsuzsa
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Laboratóriumi Medicina Intézet
dc.contributor.authorBaah, Mary
dc.contributor.departmentDE--Általános Orvostudományi Kar
dc.date.accessioned2023-11-20T07:47:01Z
dc.date.available2023-11-20T07:47:01Z
dc.date.created2023-04-06
dc.description.abstractThe study investigated the effects of de novo anti-HLA donor-specific antibodies (DSAs) on kidney transplant recipients. Twenty-one patients with DSAs and nineteen without were observed, aiming to understand how DSAs might cause endothelial damage and potentially lead to increased blood clotting. Blood samples from both groups were analyzed for markers like CRP, von Willebrand factor antigen, soluble E selectin, and thrombin generation. The research sought to uncover whether DSAs play a role in triggering endothelial injury and provoking hypercoagulability by examining thrombin production and related clotting parameters in these transplant patients.
dc.description.courseáltalános orvos
dc.description.courselangangol
dc.description.degreeegységes, osztatlan
dc.format.extent37
dc.identifier.urihttps://hdl.handle.net/2437/360905
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectThrombin Generation
dc.subjectKidney Transplantation
dc.subjectABMR
dc.subject.dspaceDEENK Témalista::Biológiai tudományok
dc.subject.dspaceDEENK Témalista::Orvostudomány
dc.titleAntibody Mediated Rejection (ABMR) after Kidney Transplantation: Diagnostic and Prognostic Markers of Hemostasis and Endothelial Cell Damage
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