New advances in the treatment of heart failure

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dc.contributor.advisorPórszász, Róbert
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorAlzeer, Abdullah Essa I
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentDrimba, László
dc.contributor.opponentSzentmiklósi, József András
dc.contributor.opponentdeptKenézy Kórház Központi Aneszteziológiai és Intenzív Terápiás Osztályhu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.date.accessioned2019-01-31T13:08:15Z
dc.date.available2019-01-31T13:08:15Z
dc.date.created2018-10-25
dc.description.abstractHeart failure is now recognised as a major and escalating public health problem in industrialised countries with ageing populations. Of all the cardiovascular diseases, heart failure is the only diagnosis increasing in both incidence and prevalence. For this reason, there is a critical need for novel targets and treatment strategies. There are four main groups of novel inotropic agents - cardiac myosin activators, Na+/K+-ATPase inhibitors, SERCA2a activators, ryanodine receptor stabilizers – which main role is emphasized in treatment of heart failure. Omecamtiv mecarbil represents an updated therapeutic approach to directly improve cardiac function and is therefore proposed as a potential new treatment of patients with systolic heart failure. Levosimendan, a calcium-sensitizing inotrope and an ATPsensitive potassium–channel opener, has several effects on the body, contributing to the recovering of patients suffering from heart failure.hu_HU
dc.description.correctorSZG
dc.description.correctortben
dc.description.correctorLB
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent36hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/263482
dc.language.isoenhu_HU
dc.subjectAAVIhu_HU
dc.subjectBNP
dc.subjectLV
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titleNew advances in the treatment of heart failurehu_HU
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