A group of six patients (five women and one male) with definite rheumatoid arthritis in the range of 53 to 80 years old took part as subject in this study. All subjects were inspected and observed to determine, localize and characterize the pain, swelling and deformities such as swan neck deformity, boutonniere deformity, Z-thumb deformity and Madelung’s deformity of the wrist and fingers. Active movements examination were performed by a goniometer to measure the range of motion (ROM) of the wrist joint during flexion/extension and radial/ulnar deviations, thumb carpo-metacarpal (CMC) joint during thumb full opposition in flexion/extension and abduction/adduction, metacarpo-phalangeal (MCP) joints during hook fist in flexion, proximal interphalangeal (PIP) and distal interphalangeal joints (DIP) during full fist and hook fist in flexion movements of the fingers. Results showed that the range of movement (ROM) was decreased in the wrist joint of all 6 participants; the thumbs full opposition was limited in 5 out of 6 patients who had Z-thumb deformity. The 5 of the participants were almost able to perform hook fist and in the case of 1 patient the hook fist was not complete. Functional exercises and physical tests of the patient’s hands and fingers during six movements: cylindrical, spherical and hook grip, pad-to-pad, tip-to-tip and pad-to-side prehension were performed to assess the quality and level of patient’s ability to implementing the task, and to detect and record the weak and/or painful movements of the hands. Our findings show that the hand function impaired in both dominant and non-dominant hand equally, but there is a conflict between our findings and other studies. Dominant hand is more affected by deformities in rheumatoid arthritis. There is a great correlation between duration of the disease and development deformities.