Current and Novel Pharmacological Management of Diabetes

A tétel rövid nézete
dc.contributor.advisorVarga, Balázs
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.authorMahdavi, Seyed Saeed
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentFenyvesi, Ferenc
dc.contributor.opponentKozma, Mariann
dc.contributor.opponentdeptDebreceni Egyetem::Gyógyszerésztudományi Kar::Gyógyszertechnológiai Tanszékhu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.date.accessioned2021-06-16T11:26:33Z
dc.date.available2021-06-16T11:26:33Z
dc.date.created2020
dc.description.abstractDiabetes mellitus is a disease with significant and rising prevalence in today’s world with high mortality, morbidity, and cost of care associated with it. In this thesis I try to cover the disease itself and the most important aspects associated with it. Afterwards all the currently approved antidiabetic pharmaceutical treatment modalities are discussed. These include, insulins, biguanides, sulfonylureas, thiazolidinediones, DPP-4 inhibitors, GLP-1 receptor agonists, SGLT2 inhibitors, α-Glucosidase inhibitors, meglitinides, bile acid sequestrant, dopamine-2 agonists, and amylin mimetics. For each drug class, its mechanism of action, available agents, route of administration, and main side effects are discussed. When available they are compared to each other and their other effects in the body, for example being cardioprotective, is mentioned as these are also amongst the selection criteria for the therapy. Next, an overview of potential future pharmaceuticals for diabetes is given by going through agents that are available only in certain countries. Finally reviewing drugs that are currently in their clinical trial and are yet to be approved but have shown promising results with their glucose lowering abilities, other protective functions, or better side effect profile.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent38hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/311171
dc.language.isoenhu_HU
dc.subjectDiabetes Mellitushu_HU
dc.subjectPharmacological managementhu_HU
dc.subject.dspaceDEENK Témalista::Orvostudomány::Farmakológiahu_HU
dc.titleCurrent and Novel Pharmacological Management of Diabeteshu_HU
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Theses (Faculty of Medicine)