The Pharmacological Basis of Botox Treatment
Absztrakt
Botox is the brand name of a toxin known as botulinum toxin. This toxin is made from the bacteria species of Clostridium botulinum. Botox given in large concentrations can cause muscle paralysis or otherwise known as botulism, which is also associated with food poisoning due to colonization of the GI tract in infants and due to infection of any wound by the bacterium of clostridium botulinum. Botulinum toxin has 7 different types known as types A, B, C (C1, C2), D, E and F. In Humans types A, B, E and F can cause clinical symptoms. Those symptoms are cervical dystonia, severe primary axillary hyperhidrosis, strabismus, neurogenic detrusor overactivity, chronic migraine, upper limb spasticity and blepharospasm. Botox is currently used in the treatment of several medical conditions, mostly in neurology, cosmetics, urology and dermatology. Despite the efficiency of Botox treatment in many clinical cases there might be some risks of severe side effects and complications.