MicroRNA in periodontal disease

A tétel rövid nézete
dc.contributor.advisorTar, Ildikó
dc.contributor.advisordeptFogorvostudományi Kar
dc.contributor.authorEshraghi, Amirhossein
dc.contributor.departmentDE--Fogorvostudományi Kar
dc.contributor.opponentEnikö, Zsuzsa Gebri
dc.contributor.opponentMolnár, Lilla
dc.contributor.opponentdeptFogorvostudományi Kar
dc.date.accessioned2025-05-05T11:13:19Z
dc.date.available2025-05-05T11:13:19Z
dc.date.created2025
dc.description.abstractThis thesis explores the role of microRNAs (miRNAs) in the pathogenesis, diagnosis, and treatment of periodontal disease, particularly chronic periodontitis. miRNAs are small non-coding RNAs that regulate gene expression and play key roles in inflammation, immune response, and tissue homeostasis. The study highlights specific miRNAs such as miR-146a, miR-155, and miR-21, which are significantly dysregulated in periodontitis and closely linked to disease severity. Through a systematic review of current literature, the thesis identifies their potential as non-invasive biomarkers in saliva and gingival crevicular fluid. It also examines the therapeutic potential of miRNA mimics and inhibitors, especially in combination with existing treatments. Personalized treatment strategies based on miRNA profiling are proposed to enhance clinical outcomes. The research underscores the promise of miRNA-based diagnostics and therapies in transforming periodontal disease management.
dc.description.coursefogorvos
dc.description.courselangangol
dc.description.degreeegységes, osztatlan
dc.format.extent37
dc.identifier.urihttps://hdl.handle.net/2437/389571
dc.language.isoen
dc.rights.infoHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectMicroRNA
dc.subjectperiodontal disease
dc.subject.dspaceMedicine
dc.titleMicroRNA in periodontal disease
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