IGF1 and IGFBP2 polymorphisms in Hungarian Yellow and broiler chickens

A tétel rövid nézete
dc.contributor.authorSzalai, Klaudia
dc.contributor.authorTempfli, Károly
dc.contributor.authorLencsés-Varga, Erika
dc.contributor.authorBali Papp, Ágnes
dc.contributor.statusPhD hallgatóhu_HU
dc.contributor.statusegyetemi oktató, kutatóhu_HU
dc.coverage.temporal2018.06.29.hu_HU
dc.date.accessioned2018-10-11T11:49:01Z
dc.date.available2018-10-11T11:49:01Z
dc.description.abstractIndigenous Hungarian Yellow hens (n=436) and Ross broilers (n=103) were genotyped for the A570C single nucleotide polymorphism (SNP) in insulin-like growth factor (IGF1) and for the G645T non-synonymous SNP in insulin-like growth factor binding protein (IGFBP2) genes. IGF1 is a member of the polypeptide hormone family with structural similarity to insulin. Concentrations of IGF1 and various polymorphisms of the gene have previously been associated with several growth traits in chickens, whereas IGFBPs can modulate the bioactivity and growth-promoting effects of circulating IGF1. PCR-RFLP method with HinfI and BseGI restriction enzymes was applied for genotyping. Significantly (P<0.05) different IGF1 and IGFBP2 allele frequencies were detected between the dual-purpose Hungarian Yellow and the broiler populations, as IGF1 C and IGFBP2 G alleles were fixed in Hungarian Yellow, while in broilers their prevalence was 0.10 and 0.92 respectively. Furthermore, IGBP2 genotype was associated (P<0.05) with live weight at 38 days, carcass weight and breast muscle weight in the broiler population. Despite its low polymorphism information content (0.12), IGFBP2 polymorphism can be valuable for selection programmes in broilers.hu_HU
dc.format.extent602hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/257575
dc.language.isoenhu_HU
dc.subjectIGF1 and IGFBP2 polymorphismshu_HU
dc.subjectHungarian Yellow chickenshu_HU
dc.subjectBroiler chickenhu_HU
dc.subject.disciplinetudományterületek::állattenyésztési tudományokhu_HU
dc.titleIGF1 and IGFBP2 polymorphisms in Hungarian Yellow and broiler chickenshu_HU
dc.typeproceedingshu_HU
Fájlok
Gyűjtemények
Wittmann Antal Növény-, Állat- és Élelmiszertudományi DI