Pharmacological Overview of Diabetes Mellitus

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dc.contributor.advisorJuhász, Béla
dc.contributor.advisordeptDepartment of Pharmacology and Pharmacotherapyhu_HU
dc.contributor.authorThomas, Elizabel Susan
dc.contributor.departmentDE--Általános Orvostudományi Karhu_HU
dc.contributor.opponentKiss, Rita
dc.contributor.opponentKurucz, Andrea
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Farmakológiai és Farmakoterápiai Intézethu_HU
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Kardiológiai Intézethu_HU
dc.date.accessioned2021-06-17T10:50:20Z
dc.date.available2021-06-17T10:50:20Z
dc.date.created2020-08-30
dc.description.abstractDiabetes mellitus is a chronic metabolic disease of persistent high blood glucose due to the absence of insulin or the lack of its effects. The incidence has been rising rapidly in recent years, due to a number of modifiable and non-modifiable risk factors such as obesity, sedentary lifestyle, age and genetics. Timely management of the glucose levels through dietary modification, physical activity and pharmacotherapy is essential to achieve glycemic control and prevent complications of the disease. Type 1 diabetics need to use insulin therapy to maintain their glucose targets. Pharmacotherapy for type 2 diabetics includes oral anti-diabetics such as metformin, SGLT-2 inhibitors, GLP-1 agonists, DPP-4 inhibitors, TZDs and SUs. Metformin is the drug of choice for treatment in combination with lifestyle modification. Novel anti-diabetic drugs such as SGLT-2 inhibitors, GLP-1 agonists or DPP-4 inhibitors can be added to reach glycemic goals. There needs to be emphasis on drugs that have a weight reducing and cardioprotective effect, without provoking hypoglycemia. Choosing the right combination of drugs which are individualized to the patient, with flexibility for adjustments, helps ensure the target glycemic parameters are reached and maintained, decreases overall cardiovascular risk, prevents complications of the disease and improves quality of life.hu_HU
dc.description.courseáltalános orvoshu_HU
dc.description.courselangangolhu_HU
dc.description.degreeegységes, osztatlanhu_HU
dc.format.extent50hu_HU
dc.identifier.urihttp://hdl.handle.net/2437/311253
dc.language.isoenhu_HU
dc.subjectPharmacologyhu_HU
dc.subjectDiabetes Mellitushu_HU
dc.subjectPharmacotherapyhu_HU
dc.subjectAnti-diabetic drugshu_HU
dc.subject.dspaceDEENK Témalista::Orvostudományhu_HU
dc.titlePharmacological Overview of Diabetes Mellitushu_HU
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