Acne pathogenesis and treatment

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Acne is a condition characterized by chronic inflammation of the pilosebaceous unit. The inflammation can be caused by abnormal keratinization which blocks the pore, excess sebum production, and the presence of Cutibacterium acnes (C. acnes). It mainly affects the adolescent population and can result in great psychological distress due to the lesions or the scarring. It ranges from mild to moderate to severe. Various treatment approaches are available including topical application of retinoids or antimicrobial drugs, another treatment approach is the systemic introduction of antibiotics or isotretinoin which is beneficial in topical resistant cases. However, the ideal approach should include psychotherapy along with medication to deal with body image distortion issues because of scars or lesions due to acne

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Acne pathogenesis
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