Setting up methodology for the investigation of temporal and spatial recruitment of inhibitory interneurons responsible for feed forward inhibition in the spinal dorsal horn.
Absztrakt
The spinal dorsal horn is a key area for sensory modulation. We attemted to identify putative inhibitory interneurons responsible for low threshold primary afferent driven inhibition tought to be resposible for controlling nociceptive information flow.
Leírás
Kulcsszavak
Nociception, Spinal cord, Gating, Dorsal horn, Inhibitory, patch clamp, calcium imaging, wide field, Vgat, gcamp, 2 photon