Synthesis of fluorine containing mannobioside for lectin binding assays

dc.contributor.advisor	Hevesi-Mezo , Erika
dc.contributor.advisordept	Gyógyszerésztudományi Kar
dc.contributor.author	Zakari , Faith
dc.contributor.department	DE--Gyógyszerésztudományi Kar
dc.date.accessioned	2026-04-26T18:58:31Z
dc.date.available	2026-04-26T18:58:31Z
dc.date.created	2026-01-15
dc.description.abstract	This thesis describes the synthesis of a fluorinated mannobioside as a probe for lectin–carbohydrate interactions. A fluorine atom was introduced at the C-2 position of mannose to study its effect on molecular recognition. The synthesis involved protected intermediates, triflate-mediated fluorination, and thioglycoside-based glycosylation. The target compound is intended for binding studies with mannose-specific lectins such as MBL and DC-SIGN. This work contributes to the use of fluorinated glycans as tools to investigate carbohydrate–protein interactions.
dc.description.course	gyógyszerész
dc.description.courselang	angol
dc.description.degree	egységes, osztatlan
dc.format.extent	32
dc.identifier.uri	https://hdl.handle.net/2437/406485
dc.language.iso	en
dc.rights.info	Hozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subject	Lectins, carbohydrates, synthesis,
dc.subject.dspace	Chemistry
dc.title	Synthesis of fluorine containing mannobioside for lectin binding assays

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