Egészségügyi Innovációs Szemle (DE-journals)

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https://hdl.handle.net/2437/291323
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Böngészés

Egészségügyi Innovációs Szemle (DE-journals) Tárgyszó szerinti böngészés "COVID-19"

Megjelenítve 1 - 4 (Összesen 4)
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    Ápolás és betegellátás alapszakos - gyógytornász szakirányon tanuló hallgatók által ellátott feladatok és a szakmai tanulmányaikhoz kapcsolódó tapasztalatok felmérése a COVID-19 elleni védekezésben
    (2023-07-15) Besenyei, Blanka; Nagy, Attila Csaba; Balajti, Ilona
    The epidemiological situation caused by COVID-19 has led to a need for help in the health care system for students of health sciences. The aim of our research is to assess the experiences of physiotherapy students in Debrecen during the protection against COVID-19. Using a questionnaire method, we wanted to collect information on the extent to which the students were able to use what they had learned and how the practical experience they had gained contributed to their professional development.
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    Ciklodextrinek szerepe a COVID-19 elleni küzdelemben
    (2022-07-18) Réti-Nagy, Katalin; Bácskay, Ildikó; Vecsernyés, Miklós; Fenyvesi, Ferenc
    Since the emergence of the SARS-CoV-2 virus in late 2019, several therapeutic possibilities have appeared to treat patients who are often in severe condition due to the pathogen. As more information  becomes available about the virus, the therapeutic strategies can be more specific. Cyclodextrins are well known molecules in the pharmaceutical industry. Due to their special structure they can be widely used in drug development. One of our main research topic is the application of cyclodextrins, so considering the current pandemic situation, it was relevant for us to summarize the role of cyclodextrin molecules in the therapy of COVID-19 disease. In the course of our literary research, we have found many interesting theories and promising developments.
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    A koronavírus és a renin-angiotenzin rendszer kapcsolata a COVID-19 elleni gyógyszerek fejlesztésének tükrében
    (2023-02-15) Gesztelyi, Rudolf
    SARS-Co-V of the Coronaviridae family emerged in 2019 in China and soon generated a pandemic. Albeit COVID-19 did not have as high death toll as some earlier pandemics, the severity and course of disease proved to be unpredictable if factors related to general health and case history of patients were considered. Thus COVID-19 due to its potentially fatal outcome and unpredictability demanded protective measures to be taken that were not sustainable in the long run (e.g. quarantining masses of people) during the early course of the pandemic (prior to the availability of vaccination and medications). Nonetheless, the vaccine for COVID-19, albeit showed efficacy, failed to reach the level of protection the former vaccines for other communicable diseases did. Additionally, available pharmaceutical treatmentregimens were not efficacious enough in preventing fatal outcome or long-term complications. These facts underscore the necessity of initiatives that seek future avenues for drug development, with special emphasis being placed on repositioning of medications with well-established use. Upon reviewing available scientific evidence four potential approaches may be identified that if repositioned could be evaluated as anti-COVID-19 agents: 1.) manipulating the a renin-angiotensin system by the use of angiotensin converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs); 2.) inhibiting the binding between human ACE2 enzyme and SARS-CoV-2 spike protein by N-acetylcysteine, or possibly quercetin; 3.) increasing the activity of ACE2 using ibuprofen; 4.) administration of prebiotics, probiotics or tryptophan to normalize SARS-CoV-2 induced dysbiotic changes of the microbiome. 
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    Role of cyclodextrins in therapeutic strategies of COVID-19
    (Health Innovation Review) Réti-Nagy, Katalin; Bácskay, Ildikó; Vecsernyés, Miklós; Fenyvesi, Ferenc