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Formulation and testing of prebiotic capsules
(Health Innovation Review) Siposné Fehér, Pálma
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Prebiotikum tartalmú kapszulák formulálása és vizsgálata
(2022-07-18) Bácskay, Ildikó; Újhelyi, Zoltán; Pető, Ágota; Kósa, Dóra; Józsa, Liza; Vasas, Gábor; Zsuga, Judit; Siposné Fehér, Pálma
Prebiotics are non-digestible food ingredients that reach the colon unchanged, serving as nutrients for bacterial strains that are beneficial to the body and helping them to multiply. The aim of the present experimental work was to formulate a capsule with a prebiotic composition. The capsule composition was formulated from different prebiotics: inulin, galacto-oligosaccharide, pectin. In addition to prebiotics, the product contains zinc citrate. The pharmacopoeia and other dosage form test of the powder mixture and capsules were examined. The average weight of the capsules, the uncompressed and compressed density of the capsule filling, the particle size distribution by sieve analysis and the fluidity of the powder mixture were determined. In addition, the homogeneous distribution of zinc citrate in the powder mixture was investigated using an analytical method. The results of the tests confirmed that the composition is technologically appropriate. The chosen manufacturing technology and sequence of operations ensure a homogeneous distribution of components and the reproducibility.