The continual lung infection caused by Pseudomonas aeruginosa in most cystic fibrosis cases is nowadays a major concern. Multiresistance has made the production of new antibiotics an urgent necessity. A new synthetic idea of the possible antibiotic structure in which ciprofloxacin is attached to a trivalentgalactose cluster has been generated by our understanding of the relationship between bacterial lectin PA-IL and D-galactose. The method is to use a series of cupper-mediated azide- alkyne “click” reaction to join together propargylatedtetraethyelene bridges, scaffold, sugar (D- galactose) and finally, the antibiotics itself.