BGP-15 containing Solid-lipid micro- and nanoparticles: Development and Characterisation

dc.contributor.advisorVasvári , Gábor
dc.contributor.advisordeptDebreceni Egyetem::Gyógyszerésztudományi Kar::Gyógyszertechnológiai Tanszék
dc.contributor.authorNguyen, Minh Huy
dc.contributor.departmentDE--Gyógyszerésztudományi Kar
dc.date.accessioned2023-05-03T08:47:39Z
dc.date.available2023-05-03T08:47:39Z
dc.date.created2023
dc.description.abstractSolid-lipid nanoparticles are tiny, spherical carriers composed of a hydrophobic core and an aqueous phase. BGP-15 is a nicotinic amidoxime derivative developed by Hungarian researchers. It is a potential antidiabetic drug candidate with cardio-, neuro-, nephro-, and photoprotective properties. During the experiment, the aim was to formulate a suitable solid-lipid micro- and nanoparticle that contains BGP-15 for controlled delivery to the site of action. Furthermore, this study was designed to evaluate the SLNs prepared by two different techniques: High shear homogenisation and Ultrasonication in terms of drug loading and entrapment efficacy, size distribution and polydispersity index.
dc.description.correctorLB
dc.description.coursegyógyszerész
dc.description.courselangangol
dc.description.degreeegységes, osztatlan
dc.format.extent32
dc.identifier.urihttps://hdl.handle.net/2437/351575
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectdrug delivery
dc.subjectnanoparticles
dc.subjectBGP-15
dc.subject.dspaceDEENK Témalista::Orvostudomány::Gyógyszerésztudomány
dc.titleBGP-15 containing Solid-lipid micro- and nanoparticles: Development and Characterisation
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