BGP-15 containing Solid-lipid micro- and nanoparticles: Development and Characterisation
dc.contributor.advisor | Vasvári , Gábor | |
dc.contributor.advisordept | Debreceni Egyetem::Gyógyszerésztudományi Kar::Gyógyszertechnológiai Tanszék | |
dc.contributor.author | Nguyen, Minh Huy | |
dc.contributor.department | DE--Gyógyszerésztudományi Kar | |
dc.date.accessioned | 2023-05-03T08:47:39Z | |
dc.date.available | 2023-05-03T08:47:39Z | |
dc.date.created | 2023 | |
dc.description.abstract | Solid-lipid nanoparticles are tiny, spherical carriers composed of a hydrophobic core and an aqueous phase. BGP-15 is a nicotinic amidoxime derivative developed by Hungarian researchers. It is a potential antidiabetic drug candidate with cardio-, neuro-, nephro-, and photoprotective properties. During the experiment, the aim was to formulate a suitable solid-lipid micro- and nanoparticle that contains BGP-15 for controlled delivery to the site of action. Furthermore, this study was designed to evaluate the SLNs prepared by two different techniques: High shear homogenisation and Ultrasonication in terms of drug loading and entrapment efficacy, size distribution and polydispersity index. | |
dc.description.corrector | LB | |
dc.description.course | gyógyszerész | |
dc.description.courselang | angol | |
dc.description.degree | egységes, osztatlan | |
dc.format.extent | 32 | |
dc.identifier.uri | https://hdl.handle.net/2437/351575 | |
dc.language.iso | en | |
dc.rights.access | Hozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében. | |
dc.subject | drug delivery | |
dc.subject | nanoparticles | |
dc.subject | BGP-15 | |
dc.subject.dspace | DEENK Témalista::Orvostudomány::Gyógyszerésztudomány | |
dc.title | BGP-15 containing Solid-lipid micro- and nanoparticles: Development and Characterisation |