Clinical benefits of mepolizumab in the therapy of severe eosinophilic asthma bronchiale

Dátum
Szerzők
Handke, Tobias
Folyóirat címe
Folyóirat ISSN
Kötet címe (évfolyam száma)
Kiadó
Absztrakt
This Thesis analyses the effect of add-on mepolizumab therapy compared to the traditional therapy plan for patients with severe eosinophilic asthma bronchiale. Mepolizumab is an Anti-Interleukin 5 (Anti IL-5) Antibody. From the Department of Pulmonology, University of Debrecen, 13 patients were investigated. Eosinophil cell count, tiffeneau index (FEV1%), Quality-of-Life as well as oral corticosteroid requirement and number of acute exacerbations were compared. Mepolizumab showed significant benefits compared to traditional therapy alone.
Leírás
Kulcsszavak
Asthma Bronchiale, Mepolizumab, Biologic Therapy, Lung, Pulmonology
Forrás