Clinical benefits of mepolizumab in the therapy of severe eosinophilic asthma bronchiale

dc.contributor.advisorBrugós, László
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Tüdőgyógyászati Tanszék
dc.contributor.authorHandke, Tobias
dc.contributor.departmentDE--Általános Orvostudományi Kar
dc.contributor.opponentFülöp, Péter
dc.contributor.opponentLieber, Attila
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Belgyógyászati Intézet::Endochrinológiai Tanszék
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Tüdőgyógyászati Tanszék
dc.date.accessioned2022-11-07T12:25:46Z
dc.date.available2022-11-07T12:25:46Z
dc.date.created2022-08-22
dc.description.abstractThis Thesis analyses the effect of add-on mepolizumab therapy compared to the traditional therapy plan for patients with severe eosinophilic asthma bronchiale. Mepolizumab is an Anti-Interleukin 5 (Anti IL-5) Antibody. From the Department of Pulmonology, University of Debrecen, 13 patients were investigated. Eosinophil cell count, tiffeneau index (FEV1%), Quality-of-Life as well as oral corticosteroid requirement and number of acute exacerbations were compared. Mepolizumab showed significant benefits compared to traditional therapy alone.
dc.description.courseáltalános orvos
dc.description.courselangangol
dc.description.degreeegységes, osztatlan
dc.format.extent31
dc.identifier.urihttps://hdl.handle.net/2437/338980
dc.language.isoen
dc.subjectAsthma Bronchiale
dc.subjectMepolizumab
dc.subjectBiologic Therapy
dc.subjectLung
dc.subjectPulmonology
dc.subject.dspaceDEENK Témalista::Orvostudomány::Belgyógyászat
dc.titleClinical benefits of mepolizumab in the therapy of severe eosinophilic asthma bronchiale
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