Clinical benefits of mepolizumab in the therapy of severe eosinophilic asthma bronchiale
dc.contributor.advisor | Brugós, László | |
dc.contributor.advisordept | Debreceni Egyetem::Általános Orvostudományi Kar::Tüdőgyógyászati Tanszék | |
dc.contributor.author | Handke, Tobias | |
dc.contributor.department | DE--Általános Orvostudományi Kar | |
dc.contributor.opponent | Fülöp, Péter | |
dc.contributor.opponent | Lieber, Attila | |
dc.contributor.opponentdept | Debreceni Egyetem::Általános Orvostudományi Kar::Belgyógyászati Intézet::Endochrinológiai Tanszék | |
dc.contributor.opponentdept | Debreceni Egyetem::Általános Orvostudományi Kar::Tüdőgyógyászati Tanszék | |
dc.date.accessioned | 2022-11-07T12:25:46Z | |
dc.date.available | 2022-11-07T12:25:46Z | |
dc.date.created | 2022-08-22 | |
dc.description.abstract | This Thesis analyses the effect of add-on mepolizumab therapy compared to the traditional therapy plan for patients with severe eosinophilic asthma bronchiale. Mepolizumab is an Anti-Interleukin 5 (Anti IL-5) Antibody. From the Department of Pulmonology, University of Debrecen, 13 patients were investigated. Eosinophil cell count, tiffeneau index (FEV1%), Quality-of-Life as well as oral corticosteroid requirement and number of acute exacerbations were compared. Mepolizumab showed significant benefits compared to traditional therapy alone. | |
dc.description.course | általános orvos | |
dc.description.courselang | angol | |
dc.description.degree | egységes, osztatlan | |
dc.format.extent | 31 | |
dc.identifier.uri | https://hdl.handle.net/2437/338980 | |
dc.language.iso | en | |
dc.subject | Asthma Bronchiale | |
dc.subject | Mepolizumab | |
dc.subject | Biologic Therapy | |
dc.subject | Lung | |
dc.subject | Pulmonology | |
dc.subject.dspace | DEENK Témalista::Orvostudomány::Belgyógyászat | |
dc.title | Clinical benefits of mepolizumab in the therapy of severe eosinophilic asthma bronchiale |