A scrape biopsy technique of the epidermis for DNA extraction from photoaging skin monitored by optical coherence tomography (OCT)

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dc.contributor.advisorRemenyik, Éva
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Bőrgyógyászati Tanszék
dc.contributor.authorGross, Mor
dc.contributor.departmentDE--Általános Orvostudományi Kar
dc.contributor.opponentGellén, Emese
dc.contributor.opponentCsanádiné Galgóczi, Erika
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Bőrgyógyászati Tanszék
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Belgyógyászati Intézet
dc.date.accessioned2023-05-03T09:04:22Z
dc.date.available2023-05-03T09:04:22Z
dc.date.created2023-02-17
dc.description.abstractSkin exposed to ultraviolet (UV) radiation might develop DNA damage and alterations in the epidermal layer, can lead to cancer. Extraction of genomic material for DNA analysis from epidermal layer in a non-invasive biopsy technique has a major role in skin cancer prediction. Scrape biopsy of the skin is a non-invasive, fast, and usually non-scaring method of epidermal layer sampling. Optical coherence tomography (OCT) in dermatology is used to identify skin structures, and allows monitoring skin damage following different procedures. The aims: To determine whether the quantity and quality of DNA isolation by scrap skin biopsy from patients with skin photoaging is suitable for DNA sequencing. In addition, to define the area and depth of biopsy using OCT device.
dc.description.correctorLB
dc.description.courseáltalános orvos
dc.description.courselangangol
dc.description.degreeegységes, osztatlan
dc.format.extent42
dc.identifier.urihttps://hdl.handle.net/2437/351595
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectDermatology
dc.subjectSkin Biopsy
dc.subjectOptical coherence tomografy (OCT)
dc.subject.dspaceDEENK Témalista::Orvostudomány
dc.titleA scrape biopsy technique of the epidermis for DNA extraction from photoaging skin monitored by optical coherence tomography (OCT)
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Theses (Faculty of Medicine)