Association between genetic polymorhisms and external apical root resorption

dc.contributor.advisorSipos, Kitti
dc.contributor.advisordeptDebreceni Egyetem::Fogorvostudományi Kar
dc.contributor.authorTaurbek, Yenglik
dc.contributor.departmentDE--Fogorvostudományi Kar
dc.contributor.opponentMartos , Renáta
dc.contributor.opponentSuta, Péter
dc.contributor.opponentdeptDebreceni Egyetem::Fogorvostudományi Kar
dc.date.accessioned2023-04-28T13:30:58Z
dc.date.available2023-04-28T13:30:58Z
dc.date.created2023-03-03
dc.description.abstractThe primary goal of the work presented was to identify an association between genetic predisposition to EARR and the clinically developed condition of EARR. The following link was established based on an analysis of 19 independent studies for various single nucleotide polymorphisms, where some showed a significant impact on the emergence of EARR while others confirmed the lack of any influence. Several single nucleotide polymorphisms must be examined and investigated further to determine their impact on the occurrence and progression of EARR. Mutations in cytokines involved in the root resorption molecular pathway were found to have a significant effect on EARR. The polymorphisms of IL-1B, IRAK-1, IL-6, P2RX7, and VDR had the greatest effect of the polymorphisms presented.
dc.description.correctorLB
dc.description.coursefogorvos
dc.description.courselangangol
dc.description.degreeegységes, osztatlan
dc.format.extent43
dc.identifier.urihttps://hdl.handle.net/2437/351302
dc.language.isoen
dc.rights.accessHozzáférhető a 2022 decemberi felsőoktatási törvénymódosítás értelmében.
dc.subjectExternal apical root resorption
dc.subjectroot resorption
dc.subjectpolymorphisms
dc.subjectRANK/RANKL/OPG
dc.subjectIncidence
dc.subjectgenetic predisposition
dc.subjectgenetic polymorphism
dc.subjectexternal root resorption
dc.subjectEARR gene
dc.subjectorthodontic treatment
dc.subjectsingle nucleotide polymorphisms
dc.subject.dspaceDEENK Témalista::Orvostudomány::Fogorvostudomány
dc.titleAssociation between genetic polymorhisms and external apical root resorption
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