Morphological and Biomolecular Analysis of Treatment Responder and Treatment Non-Responder Chronic Wounds

A tétel rövid nézete
dc.contributor.advisorSzabó, Éva
dc.contributor.advisordeptDebreceni Egyetem::Általános Orvostudományi Kar::Bőrgyógyászati Tanszék
dc.contributor.authorJefia, Oghenevese
dc.contributor.departmentDE--Általános Orvostudományi Kar
dc.contributor.opponentSzentkereszty, Zsolt
dc.contributor.opponentGáspár, Krisztián
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Sebészeti Intézet
dc.contributor.opponentdeptDebreceni Egyetem::Általános Orvostudományi Kar::Bőrgyógyászati Tanszék
dc.date.accessioned2022-11-07T12:03:48Z
dc.date.available2022-11-07T12:03:48Z
dc.date.created2022-08-25
dc.description.abstractTo better understand the factors affecting wound healing, we investigated the morphology of therapy-responder and therapy-non-responder chronic wounds and the role of two important biomolecules, TGFβ1 (transforming growth factor β1) and the VEGF (vascular endothelial growth factor). We obtained tissue samples from venous ulcers, and from healthy skins as controls. Histological and immunohistological examinations were carried out. Clear morphological differences can be detected during histological analysis of the therapy responder, non-responder ulcer’s edge and the control skin. The immunohistological staining for TGFβ1 showed more intensive positive reactions in the responder group, and milder reaction in the non-responders. Staining for VEGF showed milder differences between the groups.
dc.description.courseáltalános orvos
dc.description.courselangangol
dc.description.degreeegységes, osztatlan
dc.format.extent33
dc.identifier.urihttps://hdl.handle.net/2437/338971
dc.language.isoen
dc.subjectWound Healing
dc.subjectChronic Wounds
dc.subjectTGFβ-1
dc.subjectVEGF
dc.subject.dspaceDEENK Témalista::Orvostudomány::Bőrgyógyászat
dc.titleMorphological and Biomolecular Analysis of Treatment Responder and Treatment Non-Responder Chronic Wounds
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Gyűjtemények
Theses (Faculty of Medicine)