Theses (Faculty of Public Health)

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https://hdl.handle.net/2437/268327

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Theses (Faculty of Public Health) Szerző szerinti böngészés "AL HERK, ANAS"

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    A Comparison Between the Worldwide Spreading Patterns of SARS-COV-1 and SARS-COV-2: A Systematic Review
    AL HERK, ANAS; Varga, Orsolya; Andrade, Carlos Alexandre Soares; DE--Népegészségügyi Kar
    This systematic review aimed to compare between the spreading patterns of SARS-COV-1 and SARS-COV-2. The critical urgency of the current COVID-19 pandemic, the difficulty to tackle down the characteristics of the two viruses, and the lack of systematic research on this subject motivated the researcher to undertake this study. The PRISMA method was employed for this study, and data was collected from multiple databases: PubMed, Web of Science, Scopus, and Google Scholar. The PECO acronym was used to create the research question, and the Mesh terms were considered for the search. Eligibility criteria were considered to include original studies conducted on human samples that compared between SARS-COV-1 and SARS-COV-2 in one or more of the following topics: incidence, prevalence, epidemiology, transmission, infection, reservoir, or incubation period. Studies were excluded if they were reviews or written in a language other than the English. The results procured when applying the search strategy were insightful. The types of studies included are a cross-sectional study, an ex vivo study, an original correspondence, and an original predictive software model. The four original studies included compared between human exposure to SARS-COV-1 and SARS-COV-2, providing information about the occurrence of the two diseases, the incidence rate in many areas around the world, the age groups that varied between children and adults, and the median age of the studied samples. Some of these studies categorized patients into gender groups to minimize bias. In addition, some of the studies provided numbers about the mortality rate, the prevalence of signs and symptoms as a direct outcome of the two viruses, as well as information about their reservoirs and their abilities to transmit from/ to humans. To conclude, it appears that the recent coronavirus outbreaks, despite the similarities between the two viruses, SARS-COV-2 was able to mutate and become more infectious than SARS-COV-1. More long-term researching and further investigations are needed.