Theses (Faculty of Dentistry)
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Tétel Korlátozottan hozzáférhető Different Motions of Rotary InstrumentsKhan, Maliha; Alexander, Juhasz; Department of Operative Dentistry and Endodontics; DE--Fogorvostudományi Kar; Laszlo, Nagy; Eniko, TothThe introduction of rotary instruments has been a major breakthrough in endodontics. This is in part, due to the NiTi composition of these instruments; which allows for successful cleaning and shaping of the root canal. The success of these instruments is primarily achieved through the different motions of the rotary instruments. These motions include the rotary and reciprocating technique which allows for lowered fatigue resistance, lowered compressive and tensile stress; improving the predictability and effectiveness of endodontic treatmentTétel Korlátozottan hozzáférhető Fixed Functional Appliance Systems in OrthodonticsChao, Michelle Hsiao-Wei; Vitályos, Géza; Debreceni Egyetem::Fogorvostudományi Kar::Gyermekfogászati és Fogszabályozási Tanszék; DE--Fogorvostudományi Kar; Hamid, Leila; Török, Judit; Debreceni Egyetem::Fogorvostudományi Kar::Gyermekfogászati és Fogszabályozási TanszékClass II malocclusion is one of the main orthodontic problems affecting the population. Through advancing the mandible in a sagittal and vertical plane using functional appliances, dentoalveolar and skeletal changes occur. Fixed functional appliances are able to correct skeletal abnormalities for growing patients or patients who have passed the maximum pubertal growth. Fixed functional appliances are classified into three groups: rigid, flexible, hybrid.Tétel Korlátozottan hozzáférhető Microsurgical techniques in regenerative periodontal therapyLavochnik, Michal; Varga, István; Department of Periodontology; Debreceni Egyetem::Fogorvostudományi Kar; DE--Fogorvostudományi Kar; Angyal, János; Czompa, Levente; Debreceni Egyetem::Fogorvostudományi KarMicrosurgery and minimally invasive surgery should be considered a true reality in periodontal regenerative surgery. Several clinical trials have shown their efficacy and predictability in the treatment of intrabony defects. In 1992 microsurgery was introduced to the field of periodontics. The main fields of application in periodontology comprise root preparation, mucogingival surgery, and crown lengthening; it helps periodontal regeneration using firm techniques such as “Entire Papilla Preservation Technique”.Tétel Korlátozottan hozzáférhető Role of biological mediators in periodontal healing responsesMatthíasdóttir, Rebekka; Angyal, János; Department of Periodontology; DE--Fogorvostudományi Kar; Hernádi, Katinka; Ildikó, Tar; Debreceni Egyetem::Fogorvostudományi Kar::Parodontológiai TanszékDuring wound healing, cells situated in the periodontal ligament communicate with each other and induce the healing process. The periodontal ligament stem cells migrate to the inflamed site and differentiate into mesenchymal origin cells in response to chemokines. Various mediators induce the healing process, such as interleukins, PDGF, TGF-b, IGF- 1, FGF-2, VEGF, and EGF. Non-coding RNAs have been found to be associated with inflammatory reactions including periodontal diseases. The important functions of cytokines and the gene expression levels in regulating PDL cells has given researchers more ideas and possibilities to use them as regenerative agents. Biological mediators are potential therapeutic agents for periodontal regeneration.Tétel Korlátozottan hozzáférhető The Importance of the Patient's Self-care of Periodontal Pocket BacteriaMivehchi, Hassan; Varga, István; Debreceni Egyetem::Fogorvostudományi Kar; DE--Fogorvostudományi Kar; Angyal, János; Hernádi, Katinka; Debreceni Egyetem::Fogorvostudományi KarPeriodontal disease is an infection that destroys the soft tissue and bone supporting the tooth Pockets form when the periodontal disease shows up, and the bones as well as tissues supporting the teeth are destroyed As a result, it is important to consider managing and controlling periodontal pockets The mechanical removal of biofilms is one of the techniques that have been employedTétel Korlátozottan hozzáférhető Probiotics in periodontal therapyChiu, Hsuan; Tar, Ildikó; DE--Fogorvostudományi KarThe use of oral probiotics has garnered more attention during the last several decades. Nevertheless, it is vital to understand that each of the suggested health advantages must be individually investigated for each bacterial strain. It seems that the oral microbiota as well as immune responses are influenced by probiotic bacteria. It has been demonstrated that different species of probiotic bacteria can improve periodontal health in humans through a variety of mechanisms. Some of these processes include manipulation of the host immune system as well as competition and suppression of the development, biofilm formation, and virulence expression of periodontopathogens.Tétel Korlátozottan hozzáférhető Periodontal aspects of EndodonticsSmagulova , Diana; Suta , Peter; Fogorvostudományi Kar::Konzerváló Fogászati nem önálló Tanszék; DE--Fogorvostudományi KarThe topic “Periodontal aspects of Endodontics” refer to the relationship and interactions between the dental pulp, root canal system, and the surrounding periodontal tissues. The presence of anatomical and functional relationship between these two entities was demonstrated by numerous studies held on this topic. Pathogenic bacteria and other irritants may migrate from the pulp to the periodontium and vice versa through physiological communication pathways such as apical foramen, dentinal tubules and lateral canals. Such exchange of pathogens often contributes into the development of the endo-periodontal lesions. Despite the presence of direct routes permitting the transmission of bacteria, the effect of periodontal lesions on the development of pulpal diseases is still controversial for many clinicians.Tétel Korlátozottan hozzáférhető Nicotine and its effects on periodontal tissueBassey-Duke, Amanda; Tar, Ildikó; Debreceni Egyetem::Fogorvostudományi Kar; DE--Fogorvostudományi Kar; Sári, Kinga; Bakos, Rudolf; Debreceni Egyetem::Fogorvostudományi KarNicotine, the chief active ingredient of tobacco, has been known since the introduction of the plant in Europe in the middle sixteenth century. Nicotine can be found in some vegetables consumed in every-day life such as eggplant, cauliflower, green tomatoes, and potatoes. Tobacco, which is the main source of nicotine, has two main forms: combustible tobacco (e.g. cigarettes) and smokeless tobacco (e.g. chewing tobacco). An average cigarette contains about 0.5 to 1.0 g of tobacco and 10 mg nicotine. On the other hand, the nicotine content of the bidis (21.2 mg/g) is much higher than the conventional cigarette. Nicotine is an alkaloid that is able to spread quickly to every part of the body as soon as it enters the circulation and can pass the blood brain barrier in just 7 seconds. The liver, lungs and the kidneys metabolizes majority of the inhaled nicotine. Pharmacological characteristics of nicotine present in cigarettes increases its addictive effect unlike the medically used nicotine products. Nicotine metabolites play a role in its addictive nature. Nicotine imposes its effect in 3 major ways, and creates physiological and pathological results in different body organs: ganglionic transmission, nicotinic acetylcholine receptors and stimulation of central nervous system. Poisoning from nicotine may occur by the ingestion of the products containing nicotine accidentally, or by ingestion of the actual tobacco by the children. 60 mg of nicotine is the fatal dose for an adult. The symptoms of nicotine poisoning can be acute and fast acting; they include nausea, abdominal pain, salivation, cold sweat, vomiting, diarrhea, and severe weakness. Other than these negative effects, nicotine will also alter the taste sensation and cause halitosis, smell impairments, attrition, and damage the wound healing process and delay it. According to the extensive studies done over the past 15 years to investigate the effects of the nicotine on periodontal damage, the odds of periodontitis occurring among smokers is much greater than non-smokers, with a ratio of 2.5 to 7 or even higher. Smokeless tobacco is not an exception from this result, and they can cause diseases such as oral carcinomas and white oral mucosal lesions. The nicotine concentration around the gingival tissue can get up to 300 times higher than in the plasma cells of a smoker (20 ng/ml), which in turn will damage the cell population of the oral cavity. Smoking produces harmful chemicals and carbon monoxide, which cause a decrease in the blood flow of the oral cavity capillaries. Nicotine can cause vasoconstriction and further halt the circulation. In smokers, dry socket develops easier than non-smokers. Although the result of the oral implant treatment is mainly under the effect of inflammation triggered by the plaque and occlusal load, smoking is also a major risk factor for the soft tissue alteration and loss in the implant area. This highlights the importance of dental professionals to educate their patients on smoking cessation.Tétel Korlátozottan hozzáférhető A review of matrix systemsPatel, Shivangi Jennika; Martos, Renáta; Debreceni Egyetem::Fogorvostudományi Kar; DE--Fogorvostudományi Kar; Marincsák, Rita; Balogh, Bettina; Debreceni Egyetem::Fogorvostudományi KarA review of matrix systems alongside their accessories; wedges and seperating rings. Comparing them from when they were first introduced to latest inventions along with tips and tricks on making restorations last longer by using Teflon Tape.Tétel Korlátozottan hozzáférhető Vasoconstrictors used in dentistryBhikha, Chirag Dinesh; Szentmiklósi, József András; Department of Pharmacology; DE--Fogorvostudományi Kar; Takács, Ildikó Erzsébet; Department of Pharmacologyvasoconstrictor agents in anesthesia can be detrimental to the health of patients if they are used improperly. However, vasoconstrictors have many advantages too as the study shows. The knowledge of the chemistry, pharmacokinetics and pharmacodynamics is essential in the bank of knowledge of the dentists and is key to learn and understand to those upcoming dentists, without which, the healthcare in society can be neglected and can cause grave complications.Tétel Korlátozottan hozzáférhető C-Shaped Root Canal SystemTaghipour, Sina; Bágyi, Kinga; Restorative Dentistry; Debreceni Egyetem::Fogorvostudományi Kar; DE--Fogorvostudományi Kar; Juhász, Alexander; Nagy, LászlóC shaped root canal is abnormal root canal morphology that all the canal orifices and root canal are connected to each other and makes C shape morphologoy from the pulp chamber to the apexTétel Korlátozottan hozzáférhető Synthesis and analysis of aminoethyl methacrylated hyaluronic acid and beta-tricalcium phosphate composite scaffold for bone tissue engineeringGhodratipour, Ali; Rente, Tünde; Debreceni Egyetem::Fogorvostudományi Kar; DE--Fogorvostudományi KarHA molecules were successfully conjugated with AEMA molecules. After UV light exposing crosslinking structure formed and β-TCP particles were embedded into the matrix of cross-linked AEMA-HA matrix. The structure of the samples and ~40% degree of substitution was confirmed by and 1H NMR results. All the samples were shown noticeable sharp edges and well-defined shapes as an evidence for the successful photopolymerization at a depth of 2 mm that can maintain their three-dimensional structure before, during and after swelling in PBS. Presence of higher β-TCP particles results in less swelling ratio. However this finding is advantageous in some dental applications (e.g. in limited space of the alveolar teeth sockets). The compressive stress investigations revealed that the composites Samples have a higher mechanical strength than pure AEMA-HA samples. Young’s modulus quantification indicates that samples containing β-TCP particles are less elastic than pure AEMA-HA samples and elasticity is reduced by higher concentration of the β-TCP particles. Major role β-TCP particles in the mechanical strength of the samples can be concluded. Scanning electron microscopy revealed homogenous porous structure of the samples with high-interconnected channels that is permeable for molecules and cells and can be vascularized in the living tissue. It clearly exhibited that a samples structures made up of AEMA-HA matrix with embedded β-TCP granules and crystals agglomerates that are pearly in shape. All produced material in this research were biocompatible and this fact was confirmed by cytotoxicity assay. Cell counting of all cell cultures at day 7 was significantly higher than day 1 while all cultures was in direct contact with produced samples. The final product of this research is a ceramic/polymeric composite material suitable for further studies in connection with living cells in vitro and in vivo, resulting to fabricate a proper mechanically stable scaffold for all application of bone tissue engineering.Tétel Korlátozottan hozzáférhető 3D in EndodonticsAmer, Muhammad Zoraiz; Tóth, Enikő; Debreceni Egyetem::Fogorvostudományi Kar; DE--Fogorvostudományi Kar; Antal, Zsuzsa; Bágyi, Kinga Ágnes; Debreceni Egyetem::Fogorvostudományi KarThis thesis is about the applications of 3D in Endodontics. There are various 3D technologies and techniques that can be used to improve the quality of treatment and make it easier and faster as well as improve the prognosis of the tooth.Tétel Korlátozottan hozzáférhető Endondontic Applications of Three-Dimensional PrintingLiu, Hsi An; Antal, Zsuzsa; Debreceni Egyetem::Fogorvostudományi Kar::Konzerváló Fogászati Tanszék; DE--Fogorvostudományi Kar; Suta, Péter; Martos, RenátaDental 3D models for diagnosis and treatment planning can assist dentists in performing more predictable, less invasive, and affordable operations on their patients. For complex anatomical structures, the use of 3D imaging, CAD/CAM software, and 3D printers provides significant advantages to meet the unique demands of the dentistry profession. The use of 3D printed guidance for canal localization during non-surgical endodontic treatment appears to be a reliable and predictable benefit. Combining Endodontics microsurgery with 3D printing improves the already exceptional results. As 3D imaging and 3D printing develop, educational and handling techniques for non-surgical and surgical endodontic treatments using these new technologies optimize operating outcomes and make treatments more manageable and more comfortable for patients.Tétel Korlátozottan hozzáférhető reflux disease and the dental consequencesBehdad, Niaz; Cseppentő, Ágnes; Pharmacology and pharmacotherapy; DE--Fogorvostudományi Kar; Pórszász, Róbert; Debreceni Egyetem::Gyógyszerésztudományi KarReflux disease is affecting oral health causing a great concern for both patient and the health care provider. There are some underlying disease that may be the cause of the symptoms to happen but the disease can happen without any underlying condition as well. managing of the dental consequences caused by the acid is the point we are focusing on here.Tétel Korlátozottan hozzáférhető Novel trends of treatment of diabetes type 2Thrasyvoulou, Andreas; Szentmiklósi, József András; DE--Fogorvostudományi KarType 2 diabetes mellitus is a chronic metabolic disorder in which prevalence has been increasing steadily all over the world. Diabetes has many oral complications such as caries, periodontal diseases, salivary disfunction, calculus in salivary glands, oral candidiasis, and mucosal lesions. During dental and oral surgical treatment, dental professionals should take care of special considerations in order to avoid hypoglycemia and promote appropriate wound healing.Tétel Korlátozottan hozzáférhető Guided Bone Regeneration in Dentoalveolar SurgeryBrahim, Rania; Tóth, Adrienn; Debreceni Egyetem::Fogorvostudományi Kar::Dentoalveoláris Sebészeti nem önálló Tanszék; DE--Fogorvostudományi Kar; D. Tóth, Etelka; Szakács, Dóra; Debreceni Egyetem::Fogorvostudományi Kar::Dentoalveoláris Sebészeti nem önálló Tanszék; Debreceni Egyetem::Fogorvostudományi Kar::Dentoalveoláris Sebészeti nem önálló TanszékGuided bone regeneration, or "GBR" is a surgical procedure that has become inevitable and necessary in dentoalveolar surgery due to the certain post-extractional bone resorption along with the outpacing growth in implant demands. GBR is a procedure performed to provide complete and continuous bone regeneration using resorbable or non-resorbable membranes.Tétel Korlátozottan hozzáférhető Access cavity in the 21th centuryHadieh, Ghamari; Suta, Péter; Debreceni Egyetem::Fogorvostudományi Kar::Konzerváló Fogászati Tanszék; DE--Fogorvostudományi Kar; Nagy, László; Bohács, JuditIn this study we understand what is the access cavity preparations and the error that might occur during this procedure. We also review the uptodate access cavity preparation methods. Inadequate access preparation can lead to a host of subsequent treatment issues and cause failure in the worst-case situation. Therefore, the implementation of minimally invasive dentistry is significant. Because it assists in the maximum preservation of the healthy dental issues of the patients and can prevent the common dental issues with the traditional dental access cavity preparations.Tétel Korlátozottan hozzáférhető Clinical aspects of tooth replantationMousavijahed, Seyedmasoud; D. Tóth, Etelka; Fogorvostudományi Kar; DE--Fogorvostudományi KarThe dentoalveolar area is frequently involved in trauma that can sometimes lead to soft tissue injury, bone fractures, tooth luxation, and fractures of teeth. Teenagers and young children suffer the significant proportion of traumatic dental injuries. Both primary and permanent teeth are at risk of injury. Among the most serious traumatic injuries, tooth avulsion is defined as the total separation of a tooth out of its place in the alveolar ridge. Regarding the exact traumatic injury suffered, a variety of therapy approaches and treatments are available. Tooth conditions along with extra-alveolar storage duration and medium condition are the variables that have the biggest consequence on the clinical outcomes and result of replanting the avulsed tooth.Tétel Korlátozottan hozzáférhető Removal of gutta-percha root canal fillingAndreou, Andreas; Nagy, László; Debreceni Egyetem::Fogorvostudományi Kar::Konzerváló Fogászati Tanszék; DE--Fogorvostudományi Kar; Bágyi, Kinga; Juhász, Alexander; Debreceni Egyetem::Fogorvostudományi Kar::Konzerváló Fogászati TanszékIn this thesis, description and comparing is made between different methods for removal of gutta-percha root canal filling. Methods that are described are hand instruments, rotary instruments, solvents, ultrasonic, laser and thermal. All of these methods can be used by themselves but its preferable that a combination of different methods is used as it gives better results.